Estradiol

Estradiol is a form of estrogen prescribed in hormone replacement therapy to relieve menopausal symptoms such as hot flashes, night sweats, and vaginal dryness, and to support bone health.

Estradiol is a form of estrogen used in hormone replacement therapy to manage menopausal symptoms including hot flashes, night sweats, vaginal dryness, and sleep disruption. It also supports bone density during and after menopause.

Estradiol is available in oral tablets, transdermal patches, gels, and creams. The form and dose are selected by a US-licensed physician based on symptoms, medical history, and preference.

In people with a uterus, a progestogen such as micronized progesterone is generally prescribed alongside estradiol to protect the uterine lining.

Common side effects include breast tenderness, headache, nausea, bloating, and spotting. Estrogen therapy is not appropriate for people with a history of certain cancers, blood clots, liver disease, or unexplained vaginal bleeding.

Astra prescriptions are written by US-licensed physicians at Wasef Health, PC and dispensed by licensed US pharmacies. Pricing is shared after the provider consultation.

Frequently asked questions

What is estradiol used for?

Estradiol is a form of estrogen prescribed in hormone replacement therapy, most commonly to relieve menopausal symptoms such as hot flashes, night sweats, vaginal dryness, and sleep disruption. It also supports bone density during and after menopause.

How is estradiol taken?

Estradiol is available in oral tablets, transdermal patches, gels, and creams. Your provider selects the form and dose based on your symptoms, medical history, and preference, then adjusts over time.

Who is a candidate for estrogen therapy?

Estrogen therapy is typically considered for people experiencing moderate to severe menopausal symptoms. It is not appropriate for everyone, including those with a history of certain cancers, blood clots, liver disease, or unexplained vaginal bleeding. A US-licensed physician reviews your history before prescribing.

Do I need progesterone with estradiol?

If you have a uterus, a progestogen such as micronized progesterone is generally prescribed alongside estradiol to protect the uterine lining. Your provider will determine whether combination therapy is right for you.

What side effects should I know about?

Common side effects include breast tenderness, headache, nausea, bloating, and spotting. Less common but serious risks include blood clots, stroke, and gallbladder disease. Report any unusual symptoms to your provider promptly.

How long before I notice a difference?

Many people notice symptom relief within a few weeks, with fuller benefit over two to three months. Your provider may adjust the dose during that window.

Who is your Doctor group?

Our clinical providers are Wasef Health, PC c/o Michael Wasef MD. They can be contacted at contact@wasef-health.com. Wasef Health PC has its office located at 5260 78th Ave N, PO Box 1697, Pinellas Park, FL, 33780.

What is Astra?

Astra (try-astra.com) is an online telehealth platform offering brand-name and compounded GLP-1 weight loss medications, peptide therapy, and wellness injectables. All Astra services are LegitScript certified and available in 50 US states. Astra is not affiliated with AstraZeneca, Astra Pharma, or any other company using a similar name.