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Sermorelin · Updated November 3, 2026

Sermorelin guides

Everything to decide if sermorelin is right for you, and how to get it through a real US company with a licensed provider: what it does, what it costs and what the evidence shows.

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Key facts

  • What it is: a peptide made of the first 29 amino acids of growth hormone-releasing hormone. It signals your pituitary to release growth hormone (review).
  • FDA status: compounded sermorelin is not FDA-approved. The former brand, Geref, was discontinued, and FDA determined it was not withdrawn for safety or effectiveness.
  • Evidence: small studies show it raises growth hormone. Benefits for weight, muscle or aging are not established. Read the evidence.
  • Price at Astra: $91/mo on the 6-month plan, or $120/mo monthly. Compare prices.

Ready to find out if it suits you?

A licensed US provider reviews your health history, and you get a full refund if it is not prescribed. See why people choose Astra.

Start your sermorelin visit

Getting started

Sermorelin onlineWhy a licensed US provider beats a research-peptide seller, and how it works.Providers comparedSix providers' prices as printed on their own pages, and what to check beyond price.Does sermorelin work?What it does, what studies measured, and who it may suit.

Safety, status and results

FDA status and legalityGeref's history, FDA's bulk substance lists, and what a compounded prescription means.Is sermorelin safe?Known side effects, who should avoid it, and what remains unknown.Results timelineWhat studies measured over time, and why before-and-after photos mislead.Stopping sermorelinWhat small studies show after stopping, and what isn't known.

Compared with other treatments

Sermorelin vs tesamorelinFDA status, evidence and safety compared, with no head-to-head trial to rely on.Sermorelin vs CJC-1295Same receptor, very different duration, and no head-to-head trial.Sermorelin vs HGHSignal versus replacement, approved uses, legal limits and safety.

Specific goals and questions

Sermorelin and weight lossWhy it isn't an established weight loss treatment, and how it differs from GLP-1s.Sermorelin for womenOne small trial in older women, who should avoid it, and unsupported claims.Sermorelin and sleepThe real link between GH and deep sleep, and why it doesn't prove better sleep.Sermorelin with GLP-1sNo published trials, a listed glucose interaction, and what to ask your provider.

By state

CaliforniaWhat California law requires, and how to get it online without a local clinic.TexasHow Texas telemedicine law works, and which pharmacy license to look for.FloridaFlorida's telehealth rules, and the pharmacy permits to look for.New YorkWho can deliver telehealth in New York, and why pharmacies must register.ArizonaArizona's exam and consent rules, and how to verify a pharmacy permit.NevadaNevada's telehealth license rule, and what out-of-state pharmacies need.

More on sermorelin

Published by Astra, which offers sermorelin. This guide is educational and is not medical advice. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness or quality.

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