GLP-1 Weight Loss in Springfield, MO: A Higher Obesity Rate Meets a $200-$500 Local Price Tag

Springfield's obesity rate against Missouri and the U.S., MO HealthNet's obesity coverage, three clinics that do publish prices, and uneven low-income access inside a regional hub.

37.7% of Springfield adults have obesity (CDC PLACES 2025 release, BRFSS 2023) 1, above Missouri's 35.3% and the roughly 32.8% U.S. rate for the same year 2. Springfield is a city of 170,596 anchoring a 496,975-person metro, with a median household income of $54,414 345.

Its uninsured rate is a genuine data gap here: the ACS profile did not surface a figure, so none is shown rather than implied.

County
Greene County
City population
170,5963
Metro population
496,9754
Adult obesity rate (2023)
37.7%1
Statewide comparison
35.3%2
Uninsured rate
Not published for this area. We do not estimate it.
Median household income
$54,4145
Clinician shortage context
Greene County has no active full-county Geographic HPSA for Primary Care or Mental Health (the last county-wide geographic designations were withdrawn in 1999) — Springfield's role as the regional hub means it isn't shortage-designated as a whole. But 5 facility/population-based HPSAs are active for Primary Care and 5 for Mental Health (HRSA BCD_HPSA_FCT_DET files, pulled 2026-08-28), including Advocates for a Healthy Community Inc (FQHC, PC score 21 / MH score 20), AIDS Project of the Ozarks (FQHC Look-Alike, PC 19 / MH 15), Ash Grove Family Medical Center (Rural Health Clinic, PC 16 / MH 16), MCFP-Springfield (federal correctional facility, PC 12 / MH 12), and a Low-Income Population HPSA covering roughly 104,000–190,000 low-income Greene County/Springfield residents (PC 16, MH 16). Shortage pressure concentrates in safety-net clinics and the low-income population, not the city as a whole.67
Specialist access
No dedicated dataset on endocrinology/obesity-medicine specialist counts for Springfield was available (data gap — flag, do not imply a hard number). Directionally: Springfield is the largest city and hospital hub in southwest Missouri (metro pop. 496,975), which structurally means better specialist density than the rural counties it draws from — but the active Low-Income Population HPSA (Primary Care and Mental Health, each scored 16) and multiple facility-level shortage designations at the city's FQHCs show real access gaps persist for lower-income residents specifically, even inside the region's largest referral center. "Good regional access, uneven local access" is the honest framing — do not issue a single access verdict.67
Medicaid coverage note
CORRECTED post fact-check: Missouri Medicaid (MO HealthNet) DOES cover GLP-1s for obesity under fee-for-service as of 2026 — Missouri is one of only 13 state Medicaid programs nationally covering GLP-1s for obesity, not just diabetes (KFF tracker, Jan. 2026, embedded dataset lists Missouri explicitly). MO HealthNet's own Preferred Drug List (dated 2026-08-01, 'PDL – Endocrine & Metabolic' tab) lists a dedicated 'GLP-1 Receptor Agonists Indicated for Obesity' class: Zepbound (tirzepatide) is preferred; Wegovy (semaglutide) is non-preferred but still covered on formulary, typically requiring step-therapy/prior authorization. Do not state PA clinical criteria for Wegovy specifically as fact — that document wasn't reviewed this pass and is a follow-up.89

MO HealthNet covers GLP-1s for obesity, which most states don't

This is the rare positive local coverage fact in this series. Missouri Medicaid (MO HealthNet) covers GLP-1s for obesity under fee-for-service as of 2026, one of only 13 state Medicaid programs nationally that do, not just for diabetes (KFF tracker, Jan. 2026, which lists Missouri explicitly) 8.

MO HealthNet's own Preferred Drug List, dated 2026-08-01, carries a dedicated "GLP-1 Receptor Agonists Indicated for Obesity" class: Zepbound (tirzepatide) is preferred, and Wegovy (semaglutide) is non-preferred but still covered on formulary, typically requiring step therapy or prior authorization 9. One caveat kept deliberately: Wegovy's obesity-specific prior-authorization criteria were not reviewed this pass, so no clinical criteria should be treated as established here.

What GLP-1 care costs in Springfield today

Springfield is unusually forthcoming on price, and the prices are high. Evolution Health & Wellness Center, at 3338 S National Ave, advertises semaglutide plans starting as low as $200/month and tirzepatide plans starting as low as $275/month. Checked 2026-08-28 10.

Kare Health & Wellness, at 1435 E Bradford Pkwy, publishes flat monthly pricing: semaglutide $249/month, tirzepatide $399/month, and retatrutide $349/month, each cancel-anytime with free monthly follow-ups included. Checked 2026-08-28 11. Nurse V Beauty+Tox, at 3433 S Campbell Ave Unit Y, prices by dosage tier: Tier 1 $300/mo (10-20 units), Tier 2 $375/mo (30 units), Tier 3 $450/mo (40 units), Tier 4 $500/mo (50 units), including labs, clinic visit, and prescription medication, with optional nutrition and fitness coaching at $200/mo more. Checked 2026-08-28 12.

Astra's price is national and flat: $68/month for semaglutide and $118/month for tirzepatide on 12-month plans, $816 and $1,416 billed annually, the same in Springfield as everywhere else.

A regional hub with uneven low-income access

Greene County has no active full-county geographic HPSA for primary care or mental health; the last county-wide geographic designations were withdrawn in 1999, which reflects Springfield's role as the regional hub. But 5 facility or population-based HPSAs are active for primary care and 5 for mental health (HRSA detail files, pulled 2026-08-28), including Advocates for a Healthy Community Inc (FQHC, primary care score 21, mental health 20), AIDS Project of the Ozarks (FQHC Look-Alike, 19 and 15), Ash Grove Family Medical Center (Rural Health Clinic, 16 and 16), MCFP-Springfield (federal correctional facility, 12 and 12), and a Low-Income Population HPSA scored 16 in each discipline 67.

No dedicated dataset on endocrinology or obesity-medicine specialist counts for Springfield was available, so no provider number is claimed here. Directionally, Springfield is the largest city and hospital hub in southwest Missouri, which structurally means better specialist density than the rural counties it draws from, while the active low-income shortage designations show real gaps persist for lower-income residents inside the region's largest referral center. Good regional access, uneven local access is the honest framing.

Telehealth removes the referral step for the people that framing describes. See the Missouri GLP-1 overview for statewide context.

Astra treats patients in Missouri through state-licensed physicians.

GLP-1 treatment options in Springfield, MO

  • Compounded tirzepatide — a dual-action GIP/GLP-1 medication, compounded by licensed pharmacies.
  • Compounded semaglutide — a GLP-1 receptor agonist, compounded by licensed pharmacies.
  • GLP-1 microdosing — physician-guided low-dose compounded tirzepatide or semaglutide.
  • Wegovy — FDA-approved brand-name semaglutide, filled by a licensed pharmacy.
  • Zepbound — FDA-approved brand-name tirzepatide, filled by a licensed pharmacy.

Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality. A licensed physician decides whether treatment is appropriate for you.

What GLP-1 treatment costs in Springfield, MO

Monthly self-pay prices published by local providers, compared with Astra's online programs and the manufacturers' own self-pay prices for brand-name drugs. Compounded and brand-name medications are different products; compounded medications are not FDA-approved.

  • Evolution Health & Wellness Center — semaglutide$200/mo
  • Evolution Health & Wellness Center — tirzepatide$275/mo
  • Kare Health & Wellness — semaglutide$249/mo
  • Kare Health & Wellness — tirzepatide$399/mo
  • Astra — compounded semaglutide$68/mo
  • Astra — compounded tirzepatide$118/mo
  • Wegovy pen — NovoCare self-pay$349/mo
  • Zepbound® — LillyDirect self-pay$299–$449/mo
Local published priceAstra onlineBrand-name, manufacturer self-payPrice range
Price data & sources
ProviderPer monthBasisSource
Evolution Health & Wellness Center — semaglutide$200per month, "starting as low as"source, checked 2026-08-28
Evolution Health & Wellness Center — tirzepatide$275per month, "starting as low as"source, checked 2026-08-28
Kare Health & Wellness — semaglutide$249per month, cancel anytimesource, checked 2026-08-28
Kare Health & Wellness — tirzepatide$399per month, cancel anytimesource, checked 2026-08-28
Astra — compounded semaglutide$68per month, 12-month planprogram page
Astra — compounded tirzepatide$118per month, 12-month planprogram page
Wegovy pen — NovoCare self-pay$349per month, standard priceprice index
Zepbound® — LillyDirect self-pay$299–$449per month, by doseprice index

Are there semaglutide or tirzepatide discounts or coupons in Springfield, MO?

Yes — online, for patients in Missouri. Astra has two current promo codes:

Compounded tirzepatide $100 off

Code

Compounded tirzepatide: code NEWSTART — $100 off. $109/mo instead of $118/mo on the 12-month plan ($1,316 billed once instead of $1,416).

Apply NEWSTART automatically →

Compounded semaglutide $30 off

Code

Compounded semaglutide: code Sema NewStart — $30 off. Applied at checkout; plans start at $68/mo on the 12-month plan ($816 billed once) before the discount.

Apply Sema NewStart automatically →

Click a button to start with the code already applied, or type the code during checkout. NEWSTART applies to the 12-month compounded tirzepatide plan. Plans are billed upfront, renew automatically and can be cancelled any time. A licensed physician decides whether treatment is appropriate; a visit does not guarantee a prescription. Compounded medications are not FDA-approved. Subscription terms · Refund policy. Last verified 2026-10-01.

All Astra promo codes · Semaglutide coupon guide · Tirzepatide coupon guide

Local options

  • Evolution Health & Wellness Center — Semaglutide plans starting as low as $200/month; tirzepatide plans starting as low as $275/month. 3338 S National Ave, Springfield, MO 65807. (417) 530-2200. https://evolutionhwc.com/medical-weight-loss (checked 2026-08-28)
  • Kare Health & Wellness (Integrative Health Care Springfield MO) — Published monthly pricing: semaglutide $249/month, tirzepatide $399/month, retatrutide $349/month, each "cancel anytime" with free monthly follow-ups included. 1435 E Bradford Pkwy, Springfield, MO 65804. (417) 881-4994. https://integrativehealthcarespringfieldmo.com/medical-weight-loss-semaglutide-tirzepatide-glp-1-springfield-missouri/ (checked 2026-08-28)
  • Nurse V Beauty+Tox — Tiered dosage pricing: Tier 1 $300/mo (10–20 units), Tier 2 $375/mo (30 units), Tier 3 $450/mo (40 units), Tier 4 $500/mo (50 units); includes labs, clinic visit, and prescription medication. Optional nutrition/fitness coaching +$200/mo. 3433 S Campbell Ave Unit Y, Springfield, MO 65807. (417) 300-5070. https://nursevbeauty.com/weight-loss (checked 2026-08-28)

Frequently asked questions

Is Astra cheaper than local weight-loss clinics in Springfield, MO?

Yes, by a wide margin. The three Springfield clinics publishing real GLP-1 prices charge $200–$500/month before add-ons: Evolution Health & Wellness (from $200/mo semaglutide, $275/mo tirzepatide), Kare Health & Wellness ($249/mo semaglutide, $399/mo tirzepatide), and Nurse V Beauty+Tox ($300–$500/mo tiered by dose), all checked 2026-08-28. Astra's national price is $68/mo for semaglutide and $118/mo for tirzepatide on a 12-month plan ($816/$1,416 billed annually) — the same price in Springfield as in every other city Astra serves.

What is the adult obesity rate in Springfield, Missouri?

37.7% of Springfield adults have obesity (crude prevalence, BRFSS 2023 via CDC PLACES), compared with 35.3% statewide and roughly 32.8% nationally. Springfield runs hotter than a state that is already above the U.S. average.

Are there GLP-1 (Ozempic, Wegovy, Zepbound) shortage-area health designations in Greene County?

There's no single county-wide shortage designation — Greene County's last full-county Geographic HPSA was withdrawn in 1999, reflecting Springfield's role as the region's hospital hub. But HRSA currently lists 5 facility/population-based Primary Care HPSAs and 5 Mental Health HPSAs active in the county, including a Low-Income Population HPSA covering an estimated 104,000–190,000 low-income residents. Shortage pressure is real but concentrated in safety-net clinics and lower-income populations, not the city overall.

Does Missouri Medicaid (MO HealthNet) cover semaglutide or tirzepatide for weight loss?

Yes. Missouri is one of only 13 states whose Medicaid program covers GLP-1s for obesity (not just diabetes) as of 2026, per KFF's tracker. MO HealthNet's Preferred Drug List (dated Aug. 1, 2026) lists Zepbound (tirzepatide) as preferred and Wegovy (semaglutide) as non-preferred-but-covered, generally subject to step therapy or prior authorization.

Where can I get tirzepatide in Springfield, MO, and what do local clinics charge?

Three Springfield clinics publish tirzepatide pricing on their own sites: Evolution Health & Wellness (from $275/mo), Kare Health & Wellness ($399/mo), and Nurse V Beauty+Tox ($300–$500/mo tiered by dose), all checked 2026-08-28. Astra's tirzepatide plan is $118/mo on a 12-month term ($1,416 billed annually) — the same nationwide, including in Springfield.

Sources

  1. CDC PLACES 2025 release (eav7-hnsx) — Springfield city obesity, BRFSS 2023 — https://data.cdc.gov/resource/eav7-hnsx.json?stateabbr=MO&measureid=OBESITY&locationname=Springfield
  2. CDC BRFSS state/national obesity prevalence (hn4x-zwk7) — Missouri and U.S., 2023 — https://data.cdc.gov/resource/hn4x-zwk7.json
  3. Census Population Estimates Program, Vintage 2024 — sub-county totals (Springfield city, MO) — https://www2.census.gov/programs-surveys/popest/datasets/2020-2024/cities/totals/sub-est2024.csv
  4. Census Population Estimates Program, Vintage 2024 — CBSA totals (Springfield, MO Metro, CBSA 44180) — https://www2.census.gov/programs-surveys/popest/datasets/2020-2024/metro/totals/cbsa-est2024-alldata.csv
  5. Census Reporter ACS 2024 1-year profile — Springfield city, MO — https://censusreporter.org/profiles/16000US2970000-springfield-mo/
  6. HRSA HPSA Primary Care facility/geography detail file — https://data.hrsa.gov/DataDownload/DD_Files/BCD_HPSA_FCT_DET_PC.csv
  7. HRSA HPSA Mental Health facility/geography detail file — https://data.hrsa.gov/DataDownload/DD_Files/BCD_HPSA_FCT_DET_MH.csv
  8. KFF — Medicaid Coverage of and Spending on GLP-1s (13-state FFS obesity coverage tracker, Jan. 2026; confirms Missouri) — https://www.kff.org/medicaid/medicaid-coverage-of-and-spending-on-glp-1s/
  9. MO HealthNet Preferred Drug List, dated 2026-08-01 — GLP-1 Receptor Agonists Indicated for Obesity class — https://dss.mo.gov/sites/mydss/files/media/file/2026/08/PDL%20Static%20Document%20%202026.08.01.xlsx
  10. Evolution Health & Wellness Center — Medical Weight Loss pricing (Springfield, MO) — https://evolutionhwc.com/medical-weight-loss
  11. Kare Health & Wellness — GLP-1 weight loss pricing (Springfield, MO) — https://integrativehealthcarespringfieldmo.com/medical-weight-loss-semaglutide-tirzepatide-glp-1-springfield-missouri/
  12. Nurse V Beauty+Tox — Weight loss injection tier pricing (Springfield, MO) — https://nursevbeauty.com/weight-loss

Last reviewed:

Educational information, not medical advice. Treatment requires evaluation by a licensed physician.